Our newest product is DOAC Stop; a vital tool for any lab troubled by the new or direct oral anticoagulants. DOAC Stop removes all DOACs from sample plasmas without affecting other tests of haemostasis. Its effect is best measured using our uniformly-sensitive RVV-based DOAC-Test reagent and it complements our HEP-Stop (HRRS) for investigating unexpectedly prolonged APTT results. For lupus anticoagulant testing we have liquid stable dRVT-LS (LA Sensitive) and dRVT-LR (LA Resistant) reagents with "LS/LR" ratios being unaffected by VKA (Warfarin) or DOACs. There is also SACT II, a non-settling alternative to the classic kaolin clotting time (KCT) reagent and the Intrinsin APTT reagents; LA Sensitive and LA-Resistant. All these can be supplied ready for use or as powders for your own reconstitution. Our factor Xa- activated clotting time (XACT) test kit detects procoagulant phospholipids such as those on microparticles and activated platelets. We can supply synthetic phospholipid blends and also other procoagulant products such as soluble ellagic acid and equine collagen.

DOAC

New or Novel Oral Anti Coagulants test

 

New or novel oral anticoagulants (DOACs) include direct inhibitors of thrombin (eg dabigatran) as well as factor Xa (eg rivaroxaban, apixaban and edoxaban). The latter are difficult to quantitate using current clotting methods and chromogenic assays for individual DOACs have been developed. DOAC test reagent is a modified phospholipid-rich dilute Russells viper venom reagent with enhanced sensititivity to the new oral anti-coagulants. The reagent is ready for use and stable for approximately 1 year stored at 4°C.

We are currently offering free samples for trial. Contact us for more details.


X9211 - 6 x 8m vials