November 2022

BIOPHEN FVIII variant (Emicizumab insensitive)

A new chromogenic method for the in vitro quantitative determination of Factor FVIII activity is currently available as RUO with ARTG listing in progress.

This reagent measures the Factor VIII activity as does the BIOPHEN FVIII:C (#221402/ #221406) but is Emicizumab insensitive. It therefore allows measuring the inhibitory activity of anti-FVIII antibodies developed in haemophiliacs treated with Emicizumab and titrating their potency.

‍

Tea with Tom

Episode 6, Tom talks about the problem of Heparin contamination in APTT testing. A previous study (link below) showed that heparin was responsible for 39% of unexpectedly prolonged APTT tests in patient samples where the patient was not taking heparin (or warfarin). Haematex offers HRRS/Antihepca for neutralizing heparin. It replaces the usual M/40 calcium chloride solution in APTT and KCT tests to virtually eliminate the effect of unfractionated heparin concentrations up to 1 u/ml in normal plasma. You can find Episode 6 of Tea with Tom, together with Tom’s other talks at: https://www.haematex.com/resources/twt

Link to study: https://doi.org/10.1093/ajcp/104.4.447

‍

Holiday closure hours

Last day for Hyphen orders - To ensure delivery before we close for the year, please email your orders to htx@haematex.com before 5pm Monday 5th December 2022

Last dispatch date - Wednesday 21st December for overnight express TNT deliveries

Haematex Offices - will be closed from Friday 23rd Dec and re-open Monday 9th January.

‍

The inevitable notification about prices increases

Thank you for your ongoing support in purchasing Hyphen-BioMed and Haematex products.

As with most other businesses, we have experienced substantial increases to operating costs and from 1st January 2023, our quality supplier Hyphen-BioMed will be increasing their prices. Our price list for 2023 will reflect these changes. Please confirm prices with us at htx@haematex.com before submitting your purchase order. Thanks for your understanding and we look forward to supplying you with you with high quality coagulation reagents in 2023.

‍

Haematex is the only Australian distributor which carries out local R&D into coagulation diagnostics. When you purchase diagnostics from us, we allocate a portion of profits towards projects such as our own locally made DOAC-Stop™, Inhibitor Tubes, research on dRVVT and lupus anticoagulants.

‍

All the team at Haematex would like to thank you for your continued support over 2022 and wish you all a safe and happy holiday season! Thanks for reading, we are grateful that we can act as your local coag news resource.

‍